Review: antileukotrienes are less effective than inhaled corticosteroids in chronic asthma.
نویسنده
چکیده
and commentary also appear in ACP Journal Club. Therapeutics EBM Volume 8 March/April 2003 49 www.evidence-basedmedicine.com group.bmj.com on June 22, 2017 Published by http://ebm.bmj.com/ Downloaded from
منابع مشابه
Review: Pharmacological treatment of airway remodeling: inhaled corticosteroids or antileukotrienes?
Chronic stable asthma is characterized by inflammation of the airway wall, with abnormal accumulation of basophils, eosinophils, lymphocytes, mast cells, macrophages, dendritic cells, and myofibroblasts. Airway inflammation is not limited to severe asthma, but is also found in mild and moderate asthma. This inflammation results in a peculiar type of lymphocytic infiltration whereby Th2 lymphocy...
متن کاملAntileukotrienes in the treatment of asthma and allergic rhinitis.
OBJECTIVES To compare leukotriene antagonists (LTA) to other groups of drugs used in asthma and allergic rhinitis treatment. SOURCES MEDLINE, LILACS and Cochrane Library. KEYWORDS leukotrienes, antileukotrienes, asthma treatment, allergic rhinitis treatment, asthma and allergic rhinitis. An attempt was made to group the main studies and reviews about this topic. SUMMARY OF THE FINDINGS LT...
متن کامل[Status of leukotrienes in the pathophysiology of asthma. Necessity for antileukotrienes treatment].
Asthma is a chronic inflammatory airway disease in which many inflammatory cells and mediators participate. Inhaled corticosteroids (ICs) are recommended as the most effective anti-inflammatory medications currently available for the treatment of asthma. However, some patients don't achieve asthma control even when these agents are used in high doses in monotherapy or in combination with long-a...
متن کاملAntileukotriene agents in asthma: the dart that kills the elephant?
THE PERSISTENCE OF AIRWAY INFLAMMATION is believed to cause the mechanical changes and symptoms of asthma. After decades of research, a new class of medication has emerged that focuses on leukotrienes, mediators of inflammation. These substances are potent inducers of bronchoconstriction, increased vascular permeability and mucus production, and they potentiate the influx of inflammatory cells ...
متن کاملCurrent recommendations for the treatment of mild asthma
Patients suffering from mild asthma are divided into intermittent or persistent classes based on frequency of symptoms and reliever medication usage. Although these terms are used as descriptors, it is important to recognize the approach of focusing on asthma control in managing asthma patients. Beta-agonists are considered first-line therapy for intermittent asthmatics. If frequent use of beta...
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ورودعنوان ژورنال:
- ACP journal club
دوره 138 2 شماره
صفحات -
تاریخ انتشار 2003